Carry On Packing Thoughts

As we get closer to leaving (15 days!) I'm starting to think more seriously about packing.  There are some things that should be in everyone's carry on and then there are, of course, lots of optional items that you might like to have with you to make the flight more comfortable.

Must/Should-Have List  (includes things I would never put in checked luggage)
* Wallet (money, credit cards, ATM card)
* Passport
* Glasses (distance, reading, sun)
* Emergency contact information (relatives, insurance, etc.)
* Keys (home and car, just in case you and your luggage don't get home simultaneously)
* Medications
* Jewelry
* Personal electronics (Ipod/MP3 player, laptop, Kindle/Nook, etc.)
* Camera
* Cellphone

Other Items to Consider
* PJs, a change of clothing and essential person hygiene items (in case you and
   your checked luggage don't arrive together - unlikely, but it could happen)
* Reading material (or other things to entertain you in flight)
* Eye mask and/or ear plugs (or noise canceling headphones)
* Guidebook
* Note pad and pen
* Snack
* Addiction comforts (cigarettes, gum, sudoku, etc.)
* Water bottle (empty - you can use a water fountain after security to fill)
* Makeup
* Wet wipes or hand sanitizer
* Tissues
* Eye drops
* Back up batteries (for personal electronics, hearing aids, etc.)
* Painkillers (just in case ... aspirin, ibuprofen, etc.)
* Hand cream or other skin moisturizer
* Personal travel pillow and/or blanket

I'm starting to need a pretty big carry on for all this stuff!